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Aiguo Wu，PhD，Professor
Date: 2018-04-09, Views: 14090

Aiguo Wu，PhD, Professor, born in August 1975, Nanchang, Jiangxi Province. Full Professor since 2009, Room A510, No 1219 Zhongguan West Road, Ningbo, Zhejiang, 315201, China.

Telephone: (0086) 574-8668-5039 (Office)

E-mail: aiguo@nimte.ac.cn or aiguowu2008@yahoo.com

Achievements:

1) Published Papers: 267+ papers published in Peer Reviewer International Journals (Chem Soc. Rev., Biomaterials, Adv. Mater., ACS Nano, PNAS, Chem. Commun., J. Mater. Chem. B, Nanoscale, Adv. Sci., Adv Health. Mater. etc.)

2) Patents: Applied 189 Chinese, International and USA Patents, Awarded 72 ones including 1 US Patent and  1 Switzerland Patent

3) Invited Presentations: 90+ invited conference presentations, 50+ invited talks

4) Citations: 13000+, H-index=60

5) Book: Nanomaterials for Tumor Targeting Theranostics, Editors: Mingqian Tan, Aiguo Wu, World Scientific Publishing, Singapore, 2015 published.

Education:

Ph.D.      Analytical Chemistry
               State Key Laboratory of Electroanalytical Chemistry
               Changchun Institute of Applied Chemistry, 
               Chinese Academy of Sciences, Changchun, Jinlin Province, China 
               Defended time: December 2003, Certificated time: March 2004 
               Dissertation: DNA, Nanoparticles and their interactions investigated by 
               scanning probe microcopy (SPM)
               Thesis Advisor: Prof./Dr. Erkang Wang and Prof. /Dr. Zhuang Li

B. S.       Department of Chemistry
               Nanchang University, Nanchang, China, July 1998
               Honor thesis: Simultaneous determination of halide and thiocyanate ions by  
               potentiometric precipitation titration and multivariate calibration
               Thesis Advisor: Prof. Yongnian Ni

Professional Experience:

1) 6/2009-Present:   Full Professor, Division of Functional Materials and Nanodevices, Ningbo Institute of Materials Technology & Engineering (NIMTE), Chinese Academy of Sciences (CAS), China.

Research Interests: (1) Thernostics based on various nanomaterials; (2) Applications of Nanomaterials for Environmental Sciences; (3) Preparation of Nanostructures based on biomacromolecules                                                        

2) 9/1998–12/2003:  Research Assistant, State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, China.

Research Interests: SPM study of the interaction of DNA and nanoparticles, nanodevices (for example, nanowire) and various nanostructures using DNA as the fabricated templates. The Principal Projects were: (1) Preparing DNA Mapping by SPM, (2) Single Nanocrystal Electrochemistry, (3) Preparing Controllable Nanowire.

Honors and Awards:

1. NIMTE, CAS President’s Award for Outstanding Research Team, 2017
2. Ningbo City First Level Prize for Science and Technology (R1/7), Ningbo City, 2016
3. CAIA Special Prize (R2/10), China, 201448. Award for Returnees Startup Program, Ministry of Human Resources and Social Security of China, 2010 
4. Award for Outstanding Talents Program, Ningbo City, 2010
5. YinGang Peng Outstanding Postgraduate Student Prize, Chinese Academy of Sciences, China, 2001
6. Honor thesis, Nanchang University, Nanchang, Jiangxi, China, and July 1998
7. A Silver Prize of Mathematics Modeling Contest for Chinese University Student, JiangXi Contest Zone, Nanchang, Jiangxi, China, 1997
8. Outstanding Undergraduate Student Awards in Nanchang University, Nanchang, Jiangxi, China, 1995-1998

Publications:  Cited >7600 times, H-index=47

  1. Yanying Li, Yuanbo Pan, Yinjie Wang, Zhenqi Jiang, Ozioma U. Akakuru, Mingli Li, Xianyun Zhang, Bo Yuan, Jie Xing, Lijia Luo, Dan Larhammar, Aiguo Wu, Juan Li*, A D-peptide ligand of neuropeptide Y receptor Y1 serves as nanocarrier traversing of the blood brain barrier and targets glioma. Nano Today 2022, 44.
  2. Yuanbo Pan, Canxin Xu, Hongzhang Deng, Qing You, Chenyang Zhao, Yanying Li, Qianqian Gao, Ozioma Udochukwu Akakuru, Juan Li*, Jianmin Zhang*, Aiguo Wu*, Xiaoyuan Chen*, Localized NIR-II laser mediated chemodynamic therapy of glioblastoma. Nano Today 2022,43 .
  3. Ting Dai, Wenming He, Shuangshuang Tu, Jinru Han, Bo Yuan, Chenyang Yao, Wenzhi Ren*, Aiguo Wu*, Black TiO2 nanoprobe-mediated mild phototherapy reduces intracellular lipid levels in atherosclerotic foam cells via cholesterol regulation pathways instead of apoptosis. Bioactive Materials 2022, 17, 18-28.
  4. Chuang Liu, Shan Sun, Qiang Feng, Gongwei Wu, Yiting Wu, Na Kong, Zhangsen Yu, Junlie Yao, Xingcai Zhang, Wei Chen, Zhongmin Tang, Yufen Xiao, Xiangang Huang, Aman Lv, Chenyang Yao, Haibo Cheng, Aiguo Wu*, Tian Xie*, and Wei Tao*, Arsenene Nanodots with Selective Killing Effects and their Low-Dose Combination with ss-Elemene for Cancer Therapy. Adv Mater 2021, 33(37), e2102054.
  5. Ozioma U. Akakuru, Chen Xu, Chuang Liu, Zihou Li, Jie Xing, Chunshu Pan, Yanying Li, Elvis I. Nosike, Zhoujing Zhang, Zubair M.Iqbal,* Jianjun Zheng*, Aiguo Wu*, Metal-Free Organo-Theranostic Nanosystem with High Nitroxide Stability and Loading for Image-Guided Targeted Tumor Therapy. ACS Nano 2021, 15(2), 3079-3097.
  6. Yuanwei Pan, Xuehua Ma, Chuang Liu, Jie Xing, Suqiong Zhou, Badri Parshad, Tanja Schwerdtle, Wenzhong Li*, Aiguo Wu*, and Rainer Haag*, Retinoic Acid-Loaded Dendritic Polyglycerol-Conjugated Gold Nanostars for Targeted Photothermal Therapy in Breast Cancer Stem Cells, ACS Nano 2021, 15(9), 15069-15084.
  7. Zhenqi Jiang, Yanying Li, Zhenni Wei, Bo Yuan, Yinjie Wang, Ozioma Udochukwu Akakuru, Yong Li, Juan Li*, Aiguo Wu*, Pressure-induced amorphous zeolitic imidazole frameworks with reduced toxicity and increased tumor accumulation improves therapeutic efficacy In vivo, Bioactive Materials 2021, 6(3), 740-748.
  8. Zheyu Shen, Ting Liu, Zhen Yang, Zijian Zhou, Wei Tang, Wenpei Fan*, Yijing Liu, Jing Mu, Ling Li, Vladimir I. Bregadze, Swadhin K. Mandal, Anna A. Druzina, Zhenni Wei, Xiaozhong Qiu*, Aiguo Wu*, Xiaoyuan Chen*. Small-sized gadolinium oxide based nanoparticles for high-efficiency theranostics of orthotopic glioblastoma. Biomaterials 2020, 235, 119783. 
  9. Zhenni Wei, Zhenqi Jiang, Chunshu Pan, Jianbi Xia, Kaiwei Xu, Ting Xue, Bo Yuan, Ozioma Udochukwu Akakuru, Chengjie Zhu, Guilong Zhang, Zheng Mao, Xiaozhong Qiu*, Aiguo Wu*, Zheyu Shen*. Ten-Gram-Scale Facile Synthesis of Organogadolinium Complex Nanoparticles for Tumor Diagnosis. Small  2020, 1906870, DOI: 10.1002/smll.201906870 .
  10. Zheyu Shen, Wenpei Fan*, Zhen Yang, Yijing Liu, Vladimir I. Bregadze, Swadhin K. Mandal, Bryant C. Yung, Lisen Lin, Ting Liu*, Wei Tang, Lingling Shan, Yuan Liu, Shoujun Zhu, Sheng Wang, Weijing Yang, L. Henry Bryant, Duong T. Nguyen, Aiguo Wu*, Xiaoyuan Chen*. Exceedingly Small Gadolinium Oxide Nanoparticles with Remarkable Relaxivities for Magnetic Resonance Imaging of Tumors. Small 2019, 1903422, DOI: 10.1002/smll.201903422.
  11. Chuang Liu, Jie Xing, Ozioma Udochukwu Akakuru, Lijia Luo, Shan Sun, Ruifen Zou, Zhangsen Yu, Qianlan Fang, and Aiguo Wu*. Nanozymes-Engineered Metal−Organic Frameworks for Catalytic Cascades-Enhanced Synergistic Cancer Therapy. Nano Letters, 2019, 19, 5674−5682.
  12. Zhenqi Jiang, Yinjie Wang, Li Sun, Bo Yuan, Yuchen Tian, Lingchao Xiang, Yanying Li, Yong Li, Juan Li∗, Aiguo Wu∗, Dual ATP and pH responsive ZIF-90 nanosystem with favorable biocompatibility and facile post-modification improves therapeutic outcomes of triple negative breast cancer in vivo, Biomaterials, 2019, 197, 41-50.
  13. Zheyu Shen, Ting Liu, Yan Li, Joseph Lau, Zhen Yang, Wenpei Fan, Zijian Zhou, Changrong Shi, Chaomin Ke, Vladimir I. Bregadze, Swadhin K. Mandal, Yijing Liu*,Zihou Li, Ting Xue, Guizhi Zhu, Jeeva Munasinghe, Gang Niu, Aiguo Wu*, and Xiaoyuan Chen*, Fenton-Reaction-Acceleratable Magnetic Nanoparticles for Ferroptosis Therapy of Orthotopic Brain Tumors, ACS Nano., 2018, 12, 11355−11365.
  14. Zheyu Shen, Jibin Song, Zijian Zhou, Bryant C. Yung, Maria A. Aronova, Yan Li, Yunlu Dai, Wenpei Fan, Yijing Liu*, Zihou Li, Huimin Ruan, Richard D. Leapman, Lisen Lin, Gang Niu, Xiaoyuan Chen*, Aiguo Wu*, Dotted Core-Shell Nanoparticles with Superhigh r1 and Very Low r2/r1 for T1-Weighted MRI of Tumors, Adv Mater., 2018, 30, 1803163.
  15. Chuang Liu, Lijia Luo, Leyong Zeng, Jie Xing, Yuanzhi Xia, Shan Sun, Luyun Zhang, ZheYu, Junlie Yao, Zhangsen Yu, Ozioma Udochukwu, Akakuru, Madiha Saeed, Aiguo Wu. *, Porous gold nanoshells on functional NH2-MOFs: facile synthesis and designable platforms for cancer multiple therapy. Small, 2018, 14, 1801851. (Featutred in Front Cover, Top 10(7) in Small in 2018/08)
  16. Zhenqi Jiang, Yuchen Tian, Dingying Shan, Yinjie Wang, Ethan Gerhard, Jianbi Xia, Rong Huang, Yan He, Aiguo Li, Jianchao Tang, Huimin Ruan, Yong Li, Juan Li*, Jian Yang, and Aiguo Wu*, pH protective Y1 receptor ligand functionalized antiphagocytosis BPLP-WPU micelles for enhanced tumor imaging and therapy with prolonged survival time, Biomaterials, 2018, 170, 70-81.
  17. Zheyu Shen, Jibin Song, Bryant C. Yung, Zijian Zhou*, Aiguo Wu*, and Xiaoyuan Chen*, Emerging Strategies of Cancer Therapy Based on Ferroptosis, Adv. Mater., 2018, 30, 201704007. (Featured in Frontspecies, Invited Review)
  18. Qiuyu Gong, Ruifen Zou, Jie Xing, Lingchao Xiang, Renshuai Zhang, and Aiguo Wu*. An Ultrasensitive Near-Infrared Fluorescent Probe Reveals Pyroglutamate Aminopeptidase 1 Can Be a New Inflammatory Cytokine, Adv. Sci., 2018, 5, 1700664.
  19. Yuanzhi Xia#, Xuehua Ma #, Junhua Gao, Guoxin Chen, Zihou Li, Xiaoxia Wu, Zhangsen Yu, Jie Xing, Li Sun, Huimin Ruan, Lijia Luo，Lingchao Xiang, Chen Dong, Wenzhi Ren, Zheyu Shen *, Aiguo Wu*. A Flexible Caterpillar-Like Gold Nanoparticle Assemblies with Ultra-Small Nanogaps for Enhanced Dual-Modal Imaging and Photothermal Therapy, Small, 2018, 14, 1800094.
  20. Zheyu Shen, Tianxiang Chen, Xuehua Ma, Wenzhi Ren, Zijian Zhou, Guizhi Zhu, Ariel Zhang, Yijing Liu, Jibin Song,* Zihou Li, Huimin Ruan, Wenpei Fan, Lisen Lin, Jeeva Munasinghe, Xiaoyuan Chen,* Aiguo Wu*. Multifunctional Theranostic Nanoparticles Based on Exceedingly Small Magnetic Iron Oxide Nanoparticles for T1‑Weighted Magnetic Resonance Imaging and Chemotherapy, ACS Nano, 2017, 11, 10992−11004.
  21. Juan Li#, Yuchen Tian#, Dingying Shan, An Gong, Leyong Zeng, Wenzhi Ren, Lin gchao Xiang, Ethan Gerhard, Jinshun Zhao, Jian Yang, Aiguo Wu *, Neuropeptide Y Y1 receptor-mediated biodegradable photoluminescent nanobubbles as ultrasound contrast agents for targeted breast cancer imaging, Biomaterials, 2017, 116, 106-117.
  22. Zheyu Shen, Aiguo Wu*, and Xiaoyuan Chen*. Current detection technologies for circulating tumor cells. Chem. Soc. Rev., 2017, 46, 2038-2056. (Invited Review, Front Inside Cover)
  23. Huimin Ruan, Xiaoxia Wu, Chengcheng Yang, Zihou Li, Yuanzhi Xia, Ting Xue, Zheyu Shen*, Aiguo Wu*. A Supersensitive CTC Analysis System Based on Triangular Silver Nanoprisms and SPION with Function of Capture, Enrichment, Detection and Release, ACS Biomaterials Science & Engineering, 2018, Accepted, DOI:10.1021/acsbiomaterials.7b00825.
  24. Madiha Saeed#, Wenzhi Ren#, Aiguo Wu*. Therapeutic Applications of Iron Oxide Based Nanoparticles in Cancer: Basic Concepts and Recent Advances, Biomaterials Science, 2018, Accepted, DOI:10.1039/c7bm00999b. (Invited Review, Featured in Back Cover)
  25. Jingyan Kang, Yujie Zhang, Zhuangwei Zhou, Xing Li*, Chen Dong, Ningyi Chen, Hongyu Liu, Lijing Miao, Paul J. Low, Zhixian Gao, Narayan S. Hosmane, Aiguo Wu*. Rapid and Sensitive Colorimetric Sensing of the Insecticide Pymetrozine Using Melamine-Modified Gold Nanoparticles, Anal Methods, 2018, Accepted, DOI:10.1039/c7ay02658g.
  26.  Ningyi Chen, Hongyu Liu, Yujie Zhang, Zhuangwei Zhou, Wenpei Fan, Guocan Yu, Zheyu Shen*, Aiguo Wu*. A colorimetric sensor based on citrate-stabilized AuNPs for rapid pesticide residue detection of terbuthylazine and dimethoate. Sensor Actuators B: Chemicals, 2018, 255, 3093-3101.
  27. Jie Xing, Qiuyu Gong*, Ruifen Zou, Zihou Li, Yuanzhi Xia, Zhangsen Yu, Yufan Ye, Lingchao Xiang, Aiguo Wu*. A novel fibroblast activation protein-targeted near-infrared fluorescent off-on probe for cancer cells detection, in vitro and in vivo imaging. J Mater. Chem B, 2018, 6, 1449-1451. (Featured in Outside Front Cover)
  28. Li Sun, Yujie Zhang,* Xiushen Ye, Haining Liu,* Huifang Zhang, Aiguo Wu*, Zhijian Wu. Removal of I − from Aqueous Solutions Using a Biomass Carbonaceous Aerogel Modified with KH-560. ACS Sustainable Chem. Eng. 2017, 5, 7700−7708
  29.  Li Wang*, Yujie Zhang, Aiguo Wu, Gang Wei*. Designed graphene-peptide nanocomposites for biosensor applications: A review. Analytica Chimica Acta 2017, 985 (2017) 24-40. 
  30. Yufan Ye, Jie Xing, Leyong Zeng, Zhangsen Yu, Tianxiang Chen*, Narayan S. Hosmane, Guangming Lu, Aiguo Wu*. Fluorescent/Magnetic Nanoprobes of High Specificity for Detection of Triple Negative Breast Cancer, Journal of Biomedical Nanotechnology, 2017, 13, 980-988.  
  31. Chen Dong, Zhuqing Wang, Yujie Zhang, Xuehua Ma, M. Zubair. Iqbal, Lijing Miao, Zhuangwei Zhou, Zheyu Shen, Aiguo Wu*. High-performance colorimetric detection of thiosulfate by using silver nanoparticles for smartphone-based analysis. ACS Sensors, 2017, 2(8),1152-1159.
  32. Wenzhi Ren, M. Zubair Iqbal, Leyong Zeng, Tianxiang Chen, Yuanwei Pan, Jinshun Zhao, Hao Yin, Lili Zhang, Jichao Zhang, Aiguo Li, Aiguo Wu*. Black TiO2 based core-shell nanocomposites as doxorubicin carriers for thermal imaging guided synergistic therapy of brease cancer. Nanoscale, 2017, 9(31), 11195-11204.
  33.  Lijia Luo, Rui Shu, Aiguo Wu*. Nanomaterial-based cancer immunotherapy. J. Mater. Chem B, 2017, 5, 5517-5531. (Invited Review, Front Cover)
  34. M. Zubair Iqbal, Wenzhi Ren, Madiha Saeed, Tianxiang Chen, Xuehua Ma, Xu Yu, Jichao Zhang, Lili Zhang, Aiguo Li, Aiguo Wu*. Facile fabrication route for binary transition-metal oxides Janus nanoparticles for cancer theranostic applications. Nano Research, 2017, DOI: 10.1007/s12274-017-1628-x.
  35. Jianjun Zheng, Wenzhi Ren, Tianxiang Chen, Yinhua Jin, Aiguo Li, Kun Yan, Yijiao Wu, Aiguo Wu*. Recent advances in superparamagnetic iron oxide based nanoprobes as multifunctional theranostic agents for breast cancer imaging and therapy. Current Medicinal Chemistry, 2017, 05144642.
  36. Leyong Zeng, Di Wu, Ying Tian, Yuanwei Pan, Aiguo Wu, Jinchao Zhang, Guangming Lu. Recent progress in 808 nm excited upconversion nanomaterials as multifunctional nanoprobes for visualized theranostics in cancers. Current Medicinal Chemistry, 2017, 20115959.
  37. Leyong Zeng, Di Wu, Ruifen Zou, Tianxiang Chen, Jinchao Zhang, Aiguo Wu*. Paramagnetic and superparamagnetic inorganic nanoparticles for T1-weighted magnetic resonance imaging. Current Medicinal Chemistry, 2017, 14124616.
  38. Zheyu Shen, Aiguo Wu*, Xiaoyuan Chen. Iron oxide nanoparticle based contrast agents for magnetic resonance imaging. Mol. Pharmaceutics, 2017, 14, 1352-1364.
  39. Zhuangwei Zhou, Yujie Zhang, Jingyan Kang, Chen Dong, Ningyi Chen, Xing Li*, Zhiyong Guo, Aiguo Wu*. Detection of herbicide glyphosates based on an anti-aggregation mechanism by using unmodified gold nanoparticles in the presence of Pb2+. Analytical Methods, 2017, 9, 2890-2896.
  40. Jie Feng, Limin Chen, Yuanzhi Xia, Jie Xing, Zihou Li, Qiuping Qian, Yan Wang, Aiguo Wu, Leyong Zeng*, Yunlong Zhou*. Bioconjugation of gold nanobipyramids for SERS detection and targeted photothermal therapy in breast cancer. ACS Biomater. Sci. Eng., 2017, 3, 608-618.
  41. Zhuqing Wang, Pengxiang Jin, Min Wang, Genhua Wu, Chen Dong, Aiguo Wu*. Biomass-derived porous carbonaceous aerogel as sorbent for oil-spill remediation. ACS Appl. Mater. Interfaces. 2016, 8, 32862-32868.
  42. Yuanzhi Xia, Xiaoxia Wu, Jingtai Zhao, Jinshun Zhao, Zihou Li, Wenzhi Ren, Yuchen Tian, Aiguo Li, Zheyu Shen*, Aiguo Wu*. Three dimensional plasmonic assemblies of AuNPs with an overall size of sub-200 nm for chemo-photothermal synergistic therapy of breast cancer. Nanoscale, 2016, 8, 18682-18692.
  43. Leyong Zeng, Yuanwei Pan, Ruifen Zou, Jinchao Zhang, Ying Tian, Zhaogang Teng, Shouju Wang, Wenzhi Ren, Xueshan Xiao, Jichao Zhang, Lili Zhang, Aiguo Li, Guangming Lu*, Aiguo Wu*. 808 nm-excited upconversion nanoprobes with low heating effect for targeted magnetic resonance imaging and high-efficacy photodynamic therapy in HER2-overexpressed breast cancer. Biomaterials, 2016, 103, 116-27.
  44. Yujie Zhang, Zhiqiang Xie, Zhuqing Wang, Xuhui Feng, Ying Wang*, Aiguo Wu*. Unveiling the Adsorption Mechanism of Zeolitic Imidazolate Framework-8 with High Efficiency for Removal of Copper Ions from Aqueous Solutions, Dalton Trans., 2016, 45, 12653-60. (Back Cover)
  45. Yuanwei Pan, Ling'e Zhang, Leyong Zeng*, Wenzhi Ren, Xueshan Xiao, Jichao Zhang, Lili Zhang, Aiguo Li, Guangming Lu*, Aiguo Wu*. Gd-based upconversion nanocarriers with yolk–shell structure for dual-modal imaging and enhanced chemotherapy to overcome multidrug resistance in breast cancer. Nanoscale, 2016, 8, 878-888.
  46. Xiaoxia Wu, Yuanzhi Xia, Youju Huang, Juan Li, Huimin Ruan, Tianxiang Chen, Liqiang Luo, Zheyu Shen*, Aiguo Wu*. Improved SERS-Active Nanoparticles with Various Shapes for CTC Detection without Enrichment Process with Supersensitivity and High Specificity. ACS Appl. Mater. Interfaces,2016,8(31), pp 19928–19938
  47. Ningyi Chen,Yujie Zhang, Hongyu Liu, Huimin Ruan, Chen Dong, Zheyu Shen*, Aiguo Wu*. A supersensitive probe for rapid colorimetric detection of nickel ion based on a sensing mechanism of anti-etching. ACS Sustainable Chem. Eng., 2016, 4, 6509-6516
  48. Ningyi Chen, Yujie Zhang, Hongyu Liu, Xiaoxia Wu, Yonglong Li, Lijing Miao, Zheyu Shen, Aiguo Wu*. High-Performance Colorimetric Detection of Hg2+ Based on Triangular Silver Nanoprisms, ACS Sensors, 2016, 1, 521-27.
  49. Zhuqing Wang*, Yaoge Huang, Min Wang, Genhua Wu, Tongmou Geng, Yingguo Zhao, Aiguo Wu*. Macroporous calcium alginate aerogel as sorbent for Pb2+ removal from water media. Journal of Environmental Chemical Engineering, 2016, 4, 3185-3192.
  50. Jingyan Kang, Yujie Zhang, Xing Li*, Lijing Miao, Aiguo Wu*. A rapid colorimetric sensor of clenbuterol based on cysteamine-modified gold nanoparticles. ACS Appl. Mater. Interfaces., 2016, 8 ,1-5.
  51. Min Wang, Zhuqing Wang, Genhua Wu, Yuanguang Zhang, Aiguo Wu*. Synthesis and application of magnetic adsorbent for mercury ions. Environmental Chemistry, 2016, 35, 540-547. 
  52. Li Wang*, Yujing Sun, Zhuang Li, Aiguo Wu, Gang Wei*. Bottom-up Synthesis and Sensor Applications of Biomimetic Nanostructures, Materials, 2016, 9, 53.
  53. Zhangsen Yu, Leyong Zeng, Aiguo Wu*. Near-infrared light responsive upconversion nanoparticles for imaging, drug delivery and therapy of cancers. Current Nanoscience, 2016, 12, 18-32. (Invited Review)
  54. Yu Xu, Zhenzhi Shi, Ling’e Zhang, Eric Michael Bratsolias Brown, Aiguo Wu*. Layered bismuth oxyhalide nanomaterials for highly efficient tumor photodynamic therapy. Nanoscale, 2016, 8, 12715-12722. 
  55. Chen Dong, Genhua Wu*, Zhuqing Wang, Wenzhi Ren,Yujie Zhang, Zheyu Shen, Tianhua Li, Aiguo Wu*, Selective colorimetric detection of Cr(III) and Cr(VI) using gallic acid capped gold nanoparticles. Dalton Trans., 2016, 45, 8347-8354. (Back Cover)
  56. Zheyu Shen, Hao Wu, Sugeun Yang, Xuehua Ma, Zihou Li, Mingqian Tan*, Aiguo Wu*. A novel Trojan-horse targeting strategy to reduce the non-specific uptake of nanocarriers by noncancerous cells. Biomaterials, 2015, 70, 1-11.
  57. Leyong Zeng, Yuanwei Pan, Shouju Wang, Xin Wang, Xinmei Zhao, Wenzhi Ren, Guangming Lu*, Aiguo Wu*. Raman reporter-coupled Agcore@Aushell nanostars for in vivo improved surface enhanced Raman scattering imaging and near-infrared-triggered photothermal therapy in breast cancers. ACS Appl. Mater. Interfaces., 2015, 7, 16781-16791.
  58. Lulu Pan, Shan Sun, Aidi Zhang, Kai Jiang, Ling Zhang, Chaoqing Dong, Qing Huang, Aiguo Wu, Hengwei Lin*. Truly fluorescent excitation-dependent carbon dots and their applications in multicolor cellular imaging and multidimensional sensing, Advanced Materials, 2015, 27, 7782-7787.
  59. Juan Li*, Yuchen Tian, Aiguo Wu*. Neuropeptide Y receptors: A promising target for cancer imaging andtherapy. Regenerative Biomaterials, 2015, 2, 215-219. (Invited Review)
  60. Leyong Zeng, Yuanwei Pan, Ying Tian, Xin Wang, Wenzhi Ren, Shouju Wang, Guangming Lu*, Aiguo Wu*. Doxorubicin-loaded NaYF4:Yb/Tm-TiO2 inorganic photosensitizers for NIR-triggered photodynamic therapy and enhanced chemotherapy in drug-resistant breast cancers. Biomaterials, 2015, 57, 93-106.
  61. Ling'e Zhang, Leyong Zeng*, Yuanwei Pan, Song Luo, Wenzhi Ren, An Gong, Xuehua Ma, Hongze Liang, Guangming Lu*, Aiguo Wu*. Inorganic photosensitizer coupled Gd-based upconversion luminescent nanocomposites for in vivo magnetic resonance imaging and near-infrared-responsive photodynamic therapy in cancers. Biomaterials, 2015, 44, 82-90. 
  62. Juan Li, Zheyu Shen, Xuehua Ma, Wenzhi Ren, Lingchao Xiang, An Gong, Tian Xia, Junming Guo, Aiguo Wu*. NeuropeptideY Y1 receptors meditate targeted delivery of anticancer drug with encapsulated nanoparticles to breast cancer cells with high selectivity and its potentialfor breast cancer therapy. ACS Appl. Mater. Interfaces., 2015, 7, 5574-5582.
  63. Leyong Zeng, Lijia Luo, Yuanwei Pan, Song Luo, Guangming Lu*, Aiguo Wu*. In vivo targeted magnetic resonance imaging and visualized photodynamic therapy in deep-tissue cancers using folic acid-functionalized superparamagnetic-upconversion nanocomposites. Nanoscale, 2015, 7, 8946-8954.
  64. M. Zubair Iqbal, Xuehua Ma, Tianxiang Chen, Ling’e Zhang, Wenzhi Ren, Lingchao Xiang, Aiguo Wu*. Silica coated super-paramagnetic iron oxide nanoparticles (SPIONPs): A new type contrast agent of T1 magnetic resonance imaging (MRI). J. Materials Chemistry B, 2015, 3, 5172-5181. (Featured in Back Cover)
  65. Wenzhi Ren, Yong Yan, Leyong Zeng, Zhenzhi Shi, An Gong, Peter Schaaf, Dong Wang*, Jinshun Zhao, Baobo Zou, Hongsheng Yu, Ge Chen*, Eric Michael Bratsolias Brown, Aiguo Wu*. A near infrared light triggered hydrogenated black TiO2 for cancer photothermal therapy, Advanced Healthcare Materials, 2015, 4,1526-1536. (Featured in Back Cover)
  66. Xiaoxia Wu, Liqiang Luo, Sugeun Yang, Xuehua Ma, Yonglong Li, Chen Dong, Yuchen Tian, Ling’e Zhang, Zheyu Shen*, Aiguo Wu*. Improved SERS nanoparticles for direct detection of circulating tumor cells in the blood. ACS Appl. Mater. Interfaces., 2015, 7, 9965-9971.
  67. Xuehua Ma, An Gong, Bin Chen, Jianjun Zheng, Tianxiang Chen, Zheyu Shen*, Aiguo Wu*. Exploring a new SPION-based MRI contrast agent with excellent water-dispersibility high specificity to cancer cells and strong MR imaging efficacy. Colloids and Surfaces B: Biointerface, 2015, 126, 44-49.
  68. Tianhua Li, Yonglong Li, Yujie Zhang, Chen Dong, Zheyu Shen*, Aiguo Wu*. A colorimetric nitrite detection system with excellent selectivity and high sensitivity based on Ag@Au nanoparticles. Analyst, 2015, 140, 1076–1081.
  69. Genhua Wu, Chen Dong, Yonglong Li, Zhuqing Wang, Yuexia Gao, Zheyu Shen*, Aiguo Wu*. A novel AgNPs-based colorimetric sensor for rapid detection of Cu2+ or Mn2+ via pH control. RSC Advances, 2015, 5, 20595–20602.
  70. Yang Du, Wenzhi Ren, Yaqian Li, Qian Zhang, Leyong Zeng, Chongwei Chi, Aiguo Wu*, Jie Tian*. The enhanced chemotherapeutic effects of doxorubicin loaded PEG coated TiO2 nanocarriers in an orthotopic breast tumor bearing mouse model. J. Mater. Chem. B, 2015, 3, 1518-1528. (Highlighted in J Mater. Chem. B. 2015 Year Article)
  71. Xuefeng Yan, Gang Niu, Jing Lin, Albert J. Jin, Hao Hu, Yuxia Tang, Yujie Zhang, Aiguo Wu, Jie Lu, Shaoliang Zhang, Peng Huang*, Baozhong Shen*, Xiaoyuan Chen*. Enhanced fluorescence imaging guided photodynamic therapy of sinoporphyrin sodium loaded graphene oxide. Biomaterials, 2015, 42, 4294-4302.
  72. Kai Jiang, Shan Sun, Ling Zhang, Yue Lu, Aiguo Wu, Congzhong Cai and Hengwei Lin*. Red, green, and blue luminescence by carbon dots: Full-color emission tuning and multicolor cellular imaging. Angewandte Chemie Int. Edition., 2015, 127, 5450-5453. (Featured in VIP paper)
  73. Zhenzhi Shi, Wenzhi Ren, An Gong, Xinmei Zhao, Yuehong Zou, Eric Michael Bratsolias Brown, Xiaoyuan Chen, Aiguo Wu*. Stability enhanced polyelectrolyte-coated gold nanorodphotosensitizer complexes for high/low power density photodynamic therapy. Biomaterials, 2014, 35, 7058-7067. 
  74. YongLong Li, Zihou Li, Yuexia Gao, An Gong, Yujie Zhang, Narayan S. Hosmane, Zheyu Shen*, Aiguo Wu*."Red-to-blue"colorimetric detection of cysteine via anti-etching of silver nanoprisms. Nanoscale, 2014, 6, 10631-10637. 
  75. Yonglong Li, Yumin Leng, Yujie Zhang, Tianhua Li, Zheyu Shen*, Aiguo Wu*. A new simple and reliable Hg2+ detection system based on anti-aggregation of unmodified gold nanoparticles in the presence of O-phenylenediamine. Sensors and Actuators B：Chemical, 2014, 200, 140-146.
  76. Jian Liao, Xinmei Zhao, Leyong Zeng, Yonghai Song, Li Wang*, Aiguo Wu*. Studies of TiO2 Nanoparticles and Their Precursors for the Photocatalytic Degradation of Dihydroxybenzenes. Biochemical and Biophysical Journal of Neutron Therapy & Cancer Treatments (BBJNCT), 2014, 2, 7pp.
  77. Zhuqing Wang, Min Wang, Genhua Wu, Dayu Wu*, Aiguo Wu*. Colorimetric detection of copper and efficient removal of heavy metal ions from water by diamine-functionalized SBA-15. Dalton Trans., 2014, 43, 8461–8468.
  78. Ruth R Magaye, Xia Yue, Baobo Zou*, Hongbo Shi, Hongsheng Yu*, Kui Liu, Xialu Lin, Jin Xu, Cui Yang, Aiguo Wu, Jinshun Zhao. Acute toxicity of nickel nanoparticles in rats after intravenous injection. International Journal of Nanomedicine, 2014, 9, 1393–1402. 
  79. Yuexia Gao, Xing Li*, Yonglong Li, Tianhua Li, Yayun Zhao, Aiguo Wu*. A simply visual and highly selective colorimetric detection of Hg2+ based on gold nanoparticles modified with 8-hydroxyquinolines and oxalates, Chemimcal Communications, 2014, 50, 6447-6450. (Featured in Back Cover)
  80. Ningning Yang, Yuexia Gao, Yujie Zhang, Zheyu Shen*, Aiguo Wu*. A new rapid colorimetric detection method of Al3+ with high sensitivity and excellent selectivity based on new mechanism of aggregation of smaller etched silver nanoparticles, Talanta, 2014, 122, 272–277.
  81. Ling Chen, Jinhua Li, Shasha Wang, Wenhui Lu, Aiguo Wu, Jaebum Choo, Lingxin Chen. FITC functionalized magnetic core-shell Fe3O4/Ag hybrid nanoparticle for selective determination of molecular biothiols, Sensors and Actuators B：Chemical, 2014, 193, 857-863.
  82. An Gong, Xuehua Ma, Lingchao Xiang, Wenzhi Ren, Zheyu Shen*, Aiguo Wu*. Improved double emulsion technology for fabricating autofluorescent microcapsules as novel ultrasonic/fluorescent dual-modality, Colloids and Surfaces B: Biointerfaces, 2014, 116, 561-567. 
  83. Wei Zhang, Bowei Li, Lingxin Chen,* Yunqing Wang, Dingxue Gao, Xuehua Ma, Aiguo Wu*. Brushing, a simple way to fabricate SERS active paper substrates. Analytical Methods, 2014, 6, 2066-2071.
  84. Junwei Xin, Xunjun Yin, Shougang Chen, Aiguo Wu*, Synthesis of uniform and stable silver nanoparticles by a gold seed-mediated growth approach in a buffer system. Journal of Experimental Nanoscience, 2014, 9, 382-390.
  85. Zheyu Shen*, Aiguo Wu, Sheng Dai. Low-positively charged thermosensitive copolymers as gene delivery vectors without toxic effect. Journal of Controlled Release, 2013, 172, 122-123.
  86. Xuehua Ma, An Gong, Lingchao Xiang, Tianxiang Chen, Yuexia Gao, Xingjie Liang, Zheyu Shen*, Aiguo Wu*. Biocompatible composite nanoparticles with large longitudinal relaxivity for targeted imaging and early diagnosis of cancer. J. Mater. Chem. B, 2013, 1, 3419-3428.
  87. Wenzhi Ren, Leyong Zeng, Zheyu Shen, Lingchao Xiang, An Gong, Jichao Zhang, Chengwen Mao, Aiguo Li, Tatjana Paunesu, Gayle E. Woloschak, Narayan S. Hosmane, Aiguo Wu*. Enhanced doxorubicin transport to multidrug resistant breast cancer cells via TiO2 nanocarriers. RSC Advances. 2013, 3, 20855-20861.
  88. Leyong Zeng*, Lingchao Xiang, Wenzhi Ren, Jianjun Zheng, Tianhua Li, Bin Chen, Jichao Zhang, Chengwen Mao, Aiguo Li, Aiguo Wu*. Multifunctional photosensitizer-conjugated core–shell Fe3O4@NaYF4:Yb/Er nanocomplexes and their applications in T2-weighted magnetic resonance/ upconversion luminescence imaging and photodynamic therapy of cancer cells. RSC Advances, 2013, 3, 13915-13925.
  89. Jiaying Xu, Hongbo Shi, Magaye Ruth, Hongsheng Yu, Lissy Lazar, Baobo Zou, Cui Yang, Aiguo Wu, Jinshun Zhao*. Acute Toxicity of Intravenously Administered Titanium Dioxide Nanoparticles in Mice. PLOS ONE. 2013, 8, 70618.
  90. Christine A. Falaschetti, Tatjana Paunesku, Jasmina Kurepa, Dhaval Nanavati, Stanley S. Chou, Mrinmoy De, MinHa Song, Jung-tak Jang, Aiguo Wu, Vinayak P. Dravid, Jinwoo Cheon, Jan Smalle and Gayle E. Woloschak*. Negatively Charged Metal Oxide Nanoparticles Interact with the 20S Proteasome and Differentially Modulate Its Biologic Functional Effects. ACS NANO. 2013, 7, 7759-7772.
  91. Shanmin Gao, Xin Liu,Tao Xu, Xuehua Ma, Zheyu Shen, Aiguo Wu, Yinghuai Zhu and Narayan S. Hosmane*. Synthesis and Characterization of Fe10BO3/Fe3O4/SiO2 and GdFeO3/Fe3O4/SiO2: Nanocomposites of Biofunctional Materials. Chemistry OPEN, 2013, 2, 88-92.
  92. Yumin Leng, Yonglong Li, An Gong, Zheyu Shen, Liang Chen*, Aiguo Wu*. Colorimetric Response of dithizone product and hexadecyl trimethyl ammonium bromide modified gold nanoparticle dispersion to 10 types of heavy metal ions: understanding the involved molecules from experiment to simulation. Langmuir, 2013, 29, 7591-7599. (Highlighted by Nature China:  http://www.natureasia.com/en/ nchina /article/10.1038/nchina.2013.61) 
  93. Yujie Zhang, Yumin Leng, Lijing Miao, Junwei Xin, Aiguo Wu*. A colorimetric detection of Pb2+ by using sodium thiosulfate and hexadecyl thimethyl ammonium bromide modified gold nanoparticles, Dalton Trans., 2013, 42, 5485-5490. 
  94. Yuexia Gao, Junwei Xin, Zheyu Shen, Wei Pan, Xing Li, Aiguo Wu*. A new rapid colorimetric detection method of Mn2+ based on tripolyphosphate modified silver nanoparticles, Sensors & Actuators: B. Chemical, 2013, 181, 288-293.  
  95. Leyong Zeng, Wenzhi Ren, Lingchao Xiang, Jianjun Zheng, Bin Chen, Aiguo Wu*, Multifunctional Fe3O4-TiO2 Nanocomposites for Magnetic Resonance Imaging and Potential Photodynamic Therapy. Nanoscale, 2013, 5, 2107-2113. 
  96. Lijing Miao, Junwei Xin, Zheyu Shen, Yujie Zhang, Haiyan Wang*, Aiguo Wu*. Exploring a new rapid colorimetric detection method of Cu2+ with high sensitivity and selectivity. Sensors & Actuators:B.Chemical, 2013, 176, 906-912.  
  97. Zhuqing Wang, Dayu Wu*, Genhua Wu, Ningning Yang, Aiguo Wu*, Modifying Fe3O4 microspheres with rhodamine hydrazide for selective detection and removal of Hg2+ ion in water. Journal of Hazardous Materials, 2013, 244, 621-627. 
  98. Xinmei Zhao, Narayan S. Hosmane, Aiguo Wu*. ortho-Phenylenediamine: An Effective Spacer to Build Highly Magnetic Fe3O4/Au Nanocomposites, ChemPhysChem, 2012, 13, 2142-2147. 
  99. Sha Lou, Jiaying Ye, Keqiang Li, Aiguo Wu*. Gold Nanoparticle-based Immunochromatographic Assay: An Influence from the Nanoparticulate Sizes, Analyst, 2012, 137, 1174-1181. 
  100. Leyong Zeng, Wenzhi Ren, Jianjun Zheng, Aiguo Wu*, Ping Cui. Synthesis of water-soluble FeOOH nanospindles and their performance for magnetic resonance imaging, Applied Surface Sciences, 2012, 258, 2570-2575. 
  101. Leyong Zeng, Wenzhi Ren, Jianjun Zheng, Ping Cui, Aiguo Wu*. Ultrasmall water-soluble metal-iron oxide nanoparticles as T1-weighted contrast agents for magnetic resonance imaging. Phys. Chem. Chem. Phys, 2012, 14, 2631-2636. 
  102. Leyong Zeng, Aiguo Wu*. Yazhuo Wang, Shiliu Pu and Jiandong Ding. An in-situ observation and relocation method of nanomaterial sample based on microscope systems. Microscopy Research and Technique, 2012, 75, 138-144. 
  103. Junwei Xin, Lijing Miao, Shougang Chen, Aiguo Wu*. Colorimetric detection of Cr3+ using tripolyphosphate modified gold nanoparticles in aqueous solutions. Analytical Methods, 2012, 4, 1259-1264. (Selected a Hot Paper by the journal)
  104. Junwei Xin, Fuqiang Zhang, Yuexia Gao, Yanyan Feng, Shougang Chen*, AiguoWu*. A rapid colorimetric detection method of trace Cr(VI) based on the redox etching of Agcore–Aushell nanoparticles at room. Talanta, 2012, 101, 122-127. 
  105. Lu Yan, Mimi Lin, Chao Zeng, Zhi Chen, Shu Zhang, Xinmei Zhao, Aiguo Wu, Yaping Wang, Jia Qu, Liming Dai, Mingming Guo and Yong Liu. Electroactive and Biocompatible Hydroxyl- Functionalized Graphene by Ball Milling. Journal of Materials Chemistry, 2012, 22, 8367-8371. 
  106. Yumin Leng, Fuqiang Zhang, Yujie Zhang, Xiaoqin Fu, Yanbo Weng, Liang Chen, Aiguo Wu∗. A rapid and sensitive colorimetric assay method for Co2+ based on the modified Au nanoparticles (NPs): Understanding the involved interactions from experiments and simulations. Talanta, 2012, 94, 271-277.
  107. Jay Blatnik, Lanette Luebke, Stephanie Simonet, Megan Nelson, Race Price, Rachael Leek, Leyong Zeng, Aiguo Wu, Eric M.B. Brown. Dye surface coating enables visible light activation of TiO2 nanoparticles leading to degradation of neighboring biological structures. Microscopy and. Microanalysis, 2012, 18, 134-142. 
  108. Hans C. Arora, Mark P. Jensen, Ye Yuan, Aiguo Wu, Stefan Vogt, Tatjana Paunesku, Gayle E. Woloschak. Nanocarriers Enhance Doxorubicin Uptake in Drug-Resistant Ovarian Cancer Cells. Cancer Research, 2012, 72, 769-778.
  109. Shiliu Pu, Aiguo Wu*, Songting Tan. Deposition of gold nanoparticles onto poly (DL-lactic acid) microbubbles using cetyltriethylammnonium bromide as a surface modification agent. Micro & Nano Letters, 2011, 6, 186-189. 
  110. Kenneth T. Thurn, Hans Arora, Tatjana Paunesku, Aiguo Wu, Eric M.B. Brown, Caroline Doty, Jeff Kremer, Gayle Woloschak. Endocytosis of titanium dioxide nanoparticles in prostate cancer PC-3M cells. Nanomedicine: Nanotechnology, Biology and Medicine, 2011, 7, 123-130. (Featured in Front Cover). 
  111. Fuqiang Zhang , Leyong Zeng, Yingxin Zhang , Haiyan Wang*, Aiguo Wu*. A Colorimetric Assay Method for Co2+ Based on Thioglycollic Acid Functionalized of Hexadecyl Trimethyl Ammonium Bromide Modified Au Nanoparticles (NPs). Nanoscale, 2011, 3, 2150-2154.
  112. Fuqiang Zhang, Leyong Zeng, Cui Yang, Junwei Xin, Haiyan Wang, Aiguo Wu*. A One-Step Colorimetric Method of Analysis Detection of Hg2+ Based on an in-Situ Formation of Au@HgS Core-Shell Structures. Analyst, 2011, 136, 2825-2830.
  113. Aiguo Wu, T. Paunesku, Z. Zhang, S. Vogt, B. Lai, J. Maser, V. Yaghmai, D. Li, R. A. Omary and G. E. Woloschak A Multimodal Nanocomposite for Biomedical Imaging. AIP Conf. Proc., 2011, 1365, 379-383. 
  114. Xunjun Yin, Shougang Chen, Aiguo Wu*. Green chemistry synthesis of gold nanoparticles using lactic acid as a reducing agent. Micro & Nano Letters, 2010, 5, 270-273.
  115. Aiguo Wu*, Ping Ou, Leyong Zeng. Biomedical applications of magnetic nanoparticles. Nano, 2010, 5, 245-270. (Review, Featured in Front Cover)
  116. Aiguo Wu, Tatjana Paunesku, Eric M. B. Brown, Angela Babbo, Cecille Cruz, Mohamed Aslam, Vinayak Dravid, Gayle E Woloschak. Titanium Dioxide Nanoparticles Assembled by DNA Molecules Hybridization and Loading of DNA Interacting Proteins, NANO, 2008, 3, 27-36.
  117. Aiguo Wu, Zhihong Jia, Andreas Schaper, Frank Noll, Norbert A. Hampp. Simultaneous Removal of Thiolated Membrane Proteins Resulting in Nanostructured Lipid Layers, Langmuir, 2006, 22, 5213-5216.
  118. Aiguo Wu, Wenlong Cheng, Zhuang Li, Junguang Jiang, Erkang Wang. Electrostatic-assembly metallized nanoparticles network by DNA template, Talanta, 2006, 68, 693-699.
  119. Aiguo Wu, Zhuang Li, Hualan Zhou, Erkang Wang. Nanoscale Structures of Circle-MgCl2 Constructed by Plasmid DNA Templates, Superlattices and Microstructures, 2005, 37, 151-161.
  120. Aiguo Wu, Lihua Yu, Zhuang Li, Huanming Yang, Erkang Wang. Atomic Force Microscope Investigation of Large-Circle DNA Molecules, Analytical Biochemistry, 2004, 315, 293-300.
  121. Aiguo Wu, Zhuang Li, Erkang Wang. DNA Network Structures on Various Solid Substrates Investigated by Atomic Force Microscopy, Analytical Sciences, 2004, 20, 1083-1086.
  122. Aiguo Wu, Gang Wei, Zhuang Li, Erkang Wang. Biological Samples Investigated by Atomic Force Microscopy (A Review in Chinese), Chinese Journal of Analytical Chemistry, 2004, 32, 1538-1543. 
  123. Aiguo Wu, Zhuang Li, Lihua Yu, Hongda Wang, Erkang Wang. A Relocated Technique of Atomic Force Microscopy (AFM) Samples and its Application in Molecular Biology, Ultramicroscopy, 2002, 92, 201-207.
  124. Aiguo Wu, Zhuang Li, Hualan Zhou, Jianping Zheng, Erkang Wang. Construction and Control of Plasmid DNA Network, Analyst, 2002, 127, 585-587.
  125. Aiguo Wu, Zhuang Li, Lihua Yu, Hongda Wang, Erkang Wang. Plasmid DNA Network on a Mica Substrate Investigated by Atomic Force Microscopy, Analytical Sciences, 2001, 17, 583-584.
  126. Hairong Ma, Chaozhi Wan, Aiguo Wu, Ahmed H. Zewail. DNA folding and melting observed in real time redefine the energy landscape, Proceedings of the National Academy of Sciences of the United States of America, 2007, 104, 712-716.
  127. Lihua Yu, Aiguo Wu, Hongda Wang, Zhuang Li. Deoxyribonucleic Acid Sample Preparation in Scanning Probe Microscopy, Chinese Journal of Analytical Chemistry (in Chinese), 2001, 29, 1470-1477. 
  128. Eric M.B. Brown, Tatjana Paunesku, Aiguo Wu, K. Ted Thurn, Benjamin Haley, Jimmy Clark, Taisa Priester, Gayle E. Woloschak. Methods for assessing DNA hybridization of peptide nucleic acid–titanium dioxide nanoconjugates. Analytical Biochemistry, 2008, 383, 226-235.
  129. Tatjana Paunesku, Tianyi Ke, Rohan Dharmakumar, Nicole Mascheri, Aiguo Wu, Barry Lai, Stefan Vogt, Jörg Maser, Kenneth Thurn, Barbara Szolc-Kowalska, Andrew Larson, Raymond C. Bergan, Reed Omary, Debiao Li, Zheng-Rong Lu, Gayle E. Woloschak. Gadolinium-conjugated TiO2-DNA oligonucleotide nanoconjugates show prolonged intracellular retention period and T1-weighted contrast enhancement in magnetic resonance images. Nanomedicine: Nanotechnology, Biology and Medicine, 2008, 4, 201-207. 
  130. Jianping Zheng, Zhuang Li, Aiguo Wu, Hualan Zhou. AFM Studies of DNA Structures on Mica in the Presence of Alkaline Earth Metal Ions, Biophysical Chemistry, 2003, 104, 37-43.
  131. Jianping Zheng, Zhuang Li, Aiguo Wu, Hualan Zhou, Hanying Bai, Yonghai Song. The Structural Transition of DNA-Tris(1,10-phenathroline) Cobalt(III) Complexes in Ethanol-Water Solution, Biochemical and Biophysical Research Communications, 2002, 299, 910-915.
  132. Lihua Yu, Zhuang Li, Aiguo Wu, Hongda Wang, Quanlin Suo, Xiaohui Bi, Baiqu Huang. The AFM Characterization of Ni(Phen)32+ Fixing Effects on DNA, Chemical Journal of Chinese Universities-Chinese (in Chinese), 2002, 23, 46-48.
  133. Jianbo Jia, Bingquan Wang, Aiguo Wu, Guangjin Cheng, Zhuang Li, Shaojun Dong. A Method to Construct a Third-Generation Horseradish Peroxidase Biosensor: Self-Assembling Gold Nanoparticles to Three-Dimensional Sol-Gel Network, Analytical Chemistry, 2002, 74, 2217-2223.
  134. Yan Shen, Jianyun Liu, Aiguo Wu, Junguang Jiang, Lihua Bi, Baifeng Liu, Zhuang Li, Shaojun Dong. Preparation of Pt Nanoparticles Assembled in Multilayer Films. Chemistry Letters, 2002, 5, 550-551.
  135. Li Wang, Yonghai Song, Aiguo Wu, Zhuang Li, Bailin Zhang, Erkang Wang. Study of Methanol Adsorption on Mica, Graphite and ITO Glass by Using Tapping Mode Atomic Force Microscopy. Applied Surface Science, 2002, 199, 67-73.
  136. Lin Xu, Hongyu Zhang, Enbo Wang, Aiguo Wu, Zhuang Li. Preparation, Characterization and Luminescence Properties of Ultrathin Films Containing Polyoxomealates. Materials Letters, 2002, 54, 452-457.
  137. Lin Xu, Hongyu Zhang, Enbo Wang, Aiguo Wu, Zhang Li. Preparation and Characterization of Photoluminescent Ultrathin Films Based on Polyoxometalates. Materials Chemistry and Physics, 2003, 77, 484-488.
  138. Chunhua Zhang, Zhenghua Yang, Mengxian Ding, Aiguo Wu, Zhuang Li. The Surface Property and Morphology of the Polyimides Having Fluorinated Main Chains for Liquid Crystal Alignment. Chinese Journal of Applied Chemistry (In Chinese), 2001, 18, 544-547. 
  139. Yongnian Ni, Aiguo Wu. Simultaneous Determination of Halide and Thiocyanate Ions by Potentiometric Precipitation Titration and Multivariate Calibration. Analytica Chimica Acta, 1999, 390, 117-123. 
  140. Min Jiang, Enbo Wang, Zhenhui Kang, Suoyuan Lian, Aiguo Wu, Zhuang Li. In Situ Controllable Synthesis of Polyoxometalate Nanoparticles in Polyelectrolyte Multilayers. Journal of Materials Chemistry, 2003, 13, 647-649.
  141. Hongyu Zhang, Lin Xu, Enbo Wang, Min Jiang, Aiguo Wu, Zhuang Li. Photochromic behavior and luminescent properties of novel hybrid organic-inorganic film doped with Preyssler's heteropoly acid H12[EuP5W30O110] and polyvinylpyrrolidone. Materials Letters, 2003, 57, 1417-1422.
  142. Yan Shen, Jianyun Liu, Aiguo Wu, Junguang Jiang, Lihua Bi, Baifeng Liu, Zhuang Li, Shaojun Dong. Preparation of multilayer films containing Pt nanoparticles on a glassy carbon electrode and application as an electrocatalyst for dioxygen reduction. Langmuir, 2003, 19, 5397-5401.
  143. Hualan Zhou, Zhuang Li, Aiguo Wu, Jianping Zheng, Jian Zhang, Shifa Wu. The influence of tip performance on scanning probe lithography. Applied Surface Science, 2004, 221, 402-407. 
  144. Jinzhong Wang, Guotong Du, Yan Ma, Baijun Zhao, Xiaotian Yang, Yuantao Zhang, Dali Liu, Wancheng Li, Hongjun Yang, Shuren Yang, Aiguo Wu, Zhuang Li. Study on NH3 doping in ZnO film grown on R-plane of sapphire substrate., Faguang Xuebao (Chinese Journal of Luminescence), 2003, 24, 335-338
  145. Min Jiang, Hong Zhang, Enbo Wang, Zhenhui Kang, Suoyuan Lian, Lin Xu, Aiguo Wu, Zhuang Li. Assembly and characterization of rare-earth-containing polyoxometalate [Eu(P2Mo17O61)2]17- and poly(allylamine hydrochloride) multilayer films. Chemical Research in Chinese Universities, 2004, 20, 15-19. 
  146. Hualan Zhou, Zhuang Li, Aiguo Wu, Gang Wei, Zhiguo Liu. Direct patterning of rhodamine 6G molecules on mica by dip-pen nanolithography. Applied Surface Sciences, 2004, 236, 18-24.
  147. Jianyun Liu, Yongdong Jin, Aiguo Wu, Zhuang Li, Shaojun Dong. Fabrication and Characterization of DNA/QPVP-Os Redox-Active Multilayer Film. Electroanalysis, 2004, 16, 1931-1937.
  148. Lin Xu, Jishuang Zhang, Weixiao Cao, Aiguo Wu, Zhuang Li. Stable multilayer films based on photoinduced interaction between polyoxometalates and diazo resin. Materials Letters, 2004, 58, 3441-3446.
  149. Min Jiang, Enbo Wang, Xiuli Wang, Aiguo Wu, Zhenhui Kang, Suoyuan Lian, Lin Xu, Zhuang Li. Self-assembly of lacunary Dawson type polyoxometalates and poly(allylamine hydrochloride) multilayer films: photoluminescent and electrochemical behavior. Applied Surface Sciences, 2005, 242,199-206. 
  150. K. Ted Thurn, Eric M. B. Brown, Aiguo Wu, Stefan Vogt, Barry Lai, Jörg Maser, Tatjana Paunesku, Gayle E. Woloschak. Nanoparticles for Applications in Cellular Imaging. Nanoscale Research Letters, 2007, 2, 430-441. (Review)
  151. Kenneth T. Thurn, Tatjana Paunesku, Aiguo Wu, Eric M. B. Brown, Barry Lai, Stefan Vogt, Jörg Maser, Mohammed Aslam, Vinayak Dravid, Raymond Bergan, Gayle E. Woloschak. Labeling TiO2 Nanoparticles with Dyes for Optical Fluorescence Microscopy and Determination of TiO2-DNA Nanoconjugate Stability. Small, 2009, 5, 1318-1325.
  152. Caroline Doty, Eric Brown, Aiguo Wu, Tatjana Paunesku, Gayle E. Woloschak. Effects of fluorescent dye coating of metal oxide nanoparticles on DNA scission. Journal of the Robert H. Lurie Cancer Center, Northwestern University, 2009, 13, 72-76.

 

I)    Patents ( A part list)

1.    A kind of cysteine detection reagent and test method.
(2013, Patent No.: CN201310367104.1)
Inventors：Aiguo Wu, Yonglong Li, Zheyu Shen
2.    A kind of ultrasonic/fluorescent double modal method of preparation of microcapsule contrast agents.
(2013, Patent No.: CN 201310755481.2)
Inventors：Aiguo Wu, An Gong, Zheyu Shen, Xuehua Ma, Lingchao Xiang.
3.    Portable food safety testing reagent and its preparation method and application. 
(2013, Patent No.: CN 201310511426.9)
Inventors：Leyong Zeng, Yujie Zhang, Aiguo Wu.
4.    Targeted therapy combination with drugs and its preparation method and application.
(2013, Patent No.: CN 201310318107.6)
Inventors：Zheyu Shen, Aiguo Wu, Xuehua Ma, An Gong, Wenzhi Ren, Juan Li.
5.    Compositions, method and kits for the detection of mercury ion.
(2013, Patent No.: CN201310091158.X)
Inventors：Aiguo Wu, Yuexia Gao, Zheyu Shen
6.    Portable food safety detection reagent and its preparation method and application
(2013, Patent No.: CN201310511426.9 )
Inventors：Aiguo Wu, Yumin Leng, Yujie Zhang
7.    A detection method of Cd2+.
(2012, Patent No.: CN20120391120.X )
Inventors：Aiguo Wu, Lijing Miao, Zheyu Shen, Leyong Zeng
8.    A detection method of Ni(III) cations.
(2012, Patent No.: CN201210310138.2 )
Inventors：Aiguo Wu, Ningning Yang, Zheyu Shen
9.    A method for detecting manganese ion.
(2012, Patent No.: CN201210310138.2)
Inventors：Aiguo Wu, Yuexia Gao, Zheyu Shen
10.    Active targeting type small interference RNA transport carrier and its preparation method.
(2012, Patent No.: CN201210475752.4)
Inventors：Zheyu Shen, Aiguo Wu, Wenzhi Ren, Xuehua Ma
11.    A kind of inorganic composite nanoparticle and its preparation method.
(2012, Patent No.: CN201210172056.6)
Inventors：Leyong Zeng, Aiguo Wu
12.    Used to test and the adsorption of mercury ion dual functional materials and their synthesis methods and applications.
(2012, Patent No.: CN201210396580.1)
Inventors：Aiguo Wu, Zhuqing Wang, Xinmei Zhao
13.    Tumor early diagnosis with invisible imaging material and its preparation method.
(2012, Patent No.: CN201210230833.8)
Inventors：Zheyu Shen, Aiguo Wu
14.    A rapid detection method of copper cations in aqueous solutions.
(2012, Patent No.: CN201210097477.7)
Inventors：Aiguo Wu, Lijing Miao, Junwei Xin
15.    Gd2O3-TiO2 composite nanoparticles and its preparation method and application.
(2012, Patent No.: CN201210539796.9)
Inventors：Aiguo Wu, Xuehua Ma, Zheyu Shen
16.    A rapid detection agent and its preparation and applications in multiple kinds of single metal cations.
(2012, Patent No.: CN201210159826.3)
Inventors：Aiguo Wu, Yumin Leng
17.    Based on tumor cells active nanoparticles for targeted drug delivery system and its constrution method
(2011, Patent No.: CN201110397312.7)
Inventors：Wenzhi Ren, Aiguo Wu
18.    A Preparation method of water soluble materials with core-shell or core-corona- shell structures.
(2011, Patent No.: CN201110000844.2)
Inventors：Aiguo Wu, Leyong Zeng, Fuqiang Zhang, Ping Cui
19.    Paramagnetic & up-conversion nanoparticulate composites: Preparation and Applications. 
(2011, Patent No.: CN201110032000.6)
Inventors：Leyong Zeng, Aiguo Wu, Ping Cui
20.    Preparation and application of water-soluble nanocomposite.
(2011, Patent No.: CN201110241124.5)
Inventors：Yingxin Zhang, Aiguo Wu, Xiuqing Nie
21.    A detection method of lead ion.
(2011, Patent No.: CN201110299385.2)
Inventors：Yujie Zhang, Aiguo Wu
22.    A high-yield synthesis method of (200) faceted gold nanorods and their applications.
(2011, Patent No.: CN201110363934.8)
Inventors：Yumin Leng, Aiguo Wu, Xunjun Yin
23.    A method for detection of Co2+ based on AuNPs solution.
(2011, Patent No.: CN201110363954.5)
Inventors：Yumin Leng, Aiguo Wu
24.    A green preparation method of silver nanoparticles with different shapes.
(2011, Patent No.: CN201110378232.7)
Inventors：Junwei Xin, Aiguo Wu
25.    A detection method of Cr(VI) cations.
(2011, Patent No.: CN201110378260.9)
Inventors：Junwei Xin, Aiguo Wu
26.    Fe3O4-TiO2 nanopcomposites: Preparation and application as contrast agents in magnetic resonance imaging.
(2010, Patent No.: CN201010039632.0)
Inventors：Aiguo Wu, Leyong Zeng
27.    A detection method of cations based on VA or VIA elemental compounds. 
(2010, Patent No.:CN 201010251278.8)
Inventors： Fuqiang Zhang, Aiguo Wu, Leyong Zeng, Ping Cui
28.    The detection method of metal ions.
 (2010, Patent No.:CN201010194041.0)
Inventors：Fuqiang zhang, Aiguo Wu, Leyong Zeng
29.    Synthesis method of nanoparticles/nanoparticle sol and their application in magnetic resonance imaging contrast agents. 
(2010, Patent No.: CN201010175917.7)
Inventors：Aiguo Wu, Leyong Zeng, Ping Cui
30.    A relocation method for nanomaterials or micro-/nanodevices.
(2009, Patent No.: CN200910152441.2).
Inventors: Aiguo Wu, and Leyong Zeng
31.    Multifunction nanoconjugates for imaging applications and targeted treatment.
(2009, Patent No.: US 8557290B2).
Inventors: Aiguo Wu, Tatjana Paunesku, Gayle E.Woloschak
32.    A preparation method for gold film used as scanning probe microscope substrates 
(2004, Patent No.: CN 200410010647.9) 
Inventors:Zhuang Li, Zhiguo Liu , Zhiyong Ma, Aiguo Wu, Hualan Zhou, and Gang Wei
33.    A horizontally dynamical molecule combing 
(2002, Patent No.: CN 02104270.5)
Inventors: Aiguo Wu, Zhuang Li, Hualan Zhou, Jianping Zheng, and Erkang Wang 
34.    A preparing method of controllable DNA network 
(2002, Patent No. CN 02104271.3) 
Inventors: Aiguo Wu, Zhuang Li, Jianping Zheng, Hualan Zhou, and Erkang Wang
35.    An AFM controllable probe holder 
(2001, Patent No.: CN 01224491. 0)
Inventors: Zhuang Li, Aiguo Wu, Erkang Wang, and Lihua Yu
36.    An AFM multiprobes holder
(2001, Patent No.: CN 01204082. 7)
Inventors: Zhuang Li, Aiguo Wu, Hongda Wang, and Lihua Yu
37.    A mechanical method for preparing controllable nanowire 
(2001, Patent No.: CN 01110205. 5)
Inventors: Zhuang Li and Aiguo Wu 
38.    A physical chemistry method for preparing controllable nanowire 
(2001, Patent No.: CN 01110206.3)
Inventors: Zhuang Li, Aiguo Wu, Erkang Wang, and Lihua Yu
39.    Preparation of controllable metal nanowire
(2001, Patent No.: CN 01140159.1)
Inventors: Zhuang Li, Hualan Zhou, Aiguo Wu, Jianping Zheng, Jing Li, and Erkang Wang
40.    An AFM probe holder 
(1999, Patent No.: CN 99256948. 6)
Inventors: Zhuang Li, Aiguo Wu, Hongda Wang, and Lihua Yu
41.    A relocated method for SPM samples 
(1999, Patent No.: CN 99126338. 3)
Inventors: Zhuang Li, Hongda Wang, Aiguo Wu, Lihua Yu, and Erkang Wang

 
II)    Pending Patents ( A part list)

1.    A solid spherical hydrophilic material, preparation method and application.
(2017, Applied NO.: CN201710447334.7)
Inventors：Fang Yang, Aiguo Wu, Li Sun
2.    Active targeting anti-brain tumor and its preparation method.
(2015, Applied NO.: CN201510535764.5)
Inventors：Juan Li, Aiguo Wu, Yuchen Tian
3.    A soil heavy metal fixatives and its preparation method and application.
(2015, Applied NO.: CN201510511727.0)
Inventors：Aiguo Wu, Hongyu Liu, Yujie Zhang
4.    A method for rapid on-time detection of metal ions based on smartphone.
(2015, Applied NO.: CN201510508573.X)
Inventors：Aiguo Wu, Chen Dong, Zheyu Shen, Zhuqing, Wang, Yujie Zhang
5.    A composite nanoparticles with Janus structure and its preparation method and application
(2015, Applied NO.: CN201510504659.5)
Inventors：M. Zubair Iqbal, Aiguo Wu, Leyong Zeng, Xuehua Ma, Tianxiang Chen
6.    Nanocomposites preparation method and the application of a core-shell structure.
(2015, Applied NO.: CN201510405522.4)
Inventors：Leyong Zeng, Aiguo Wu
7.    A composite meterial based on Surface-enhanced Raman Scattering technique and its preparation method.
(2015, Applied NO.: CN201510351619.1)
Inventors：Zheyu Shen, Aiguo Wu, Xiaoxia Wu, Yujie Zhang, Huimin Ruan
8.    A composite meterial with Surface-enhanced Raman Scattering technique and its preparation method.
(2015, Applied NO.: CN201510169894.1)
Inventors：Zheyu Shen, Aiguo Wu, Xiaoxia Wu
9.    A nuclear magnetic resonance (NMR) methods of rapid detection of metal ions and small molecules.
(2015, Applied NO.: CN201510107195.4)
Inventors：Aiguo Wu, Ningyi Chen, Yuejie Zhang
10.    A kind of magnetic nanoparticles, preparation method and application.
(2014, Applied No.: CN201410203774.4)
Inventors：Muhammad Zubair Iqbal, Aiguo Wu, Xuehua Ma
11.    A tumor treatment composite nanometer material and its preparation.
(2014, Applied No.: CN201410175018.5)
Inventors：Wenzhi Ren, Aiguo Wu
12.    The initiative targeted anti-tumor drugs and its preparation method.
(2014, Applied No.: PCT/CN2014/075727)
Inventors：Juan Li, Aiguo Wu
13.    A kind of imaging materials, the preparation methods and applications.
(2014, Applied No.: 201410398464.2)
Inventors：Tianxiang Chen, Aiguo Wu, An Gong
14.    A new type of imaging materials and its preparation method and application.
(2014, Applied No.: CN201410430551.1)
Inventors：Tianxiang Chen, Aiguo Wu
15.    A bismuth matrix composite nanometer material and its diagnosis and treatment of tumor.
(2014, Applied No.: CN201410788424.9)
Inventors：Aiguo Wu, Zhenzhi Shi, Yu xu
16.    A bivalent mercury ion detection reagent combination and test methods.
(2013, Applied No.: CN201310382118.0)
Inventors：Aiguo Wu, Yonglong Li, Zheyu Shen
17.    The initiative targeted anti-tumor drugs and its preparation method.
(2013, Applied No.: CN201310407938.0)
Inventors：Juan Li, Aiguo Wu
18.    Three of its preparation methods and used for the preparation of nanometer compound medicine combination USES for the treatment of tumor
(2013, Applied No.: CN201310103775.7)
Inventors：Wenzhi Ren, Aiguo Wu, Leyong Zeng, Zheyu Shen, Xuehua Ma
19.    A trivalent aluminium ion detection reagent and test method.
(2013, Applied No.: CN201310386230.1)
Inventors：Aiguo Wu, Ningning Yang, Yuexia Gao. 
20.    Actively targeted delivery vectors of siRNA and the fabrication method.
(2012, Applied No.: PCT/CN2013/070362)
Inventors： Zheyu Shen, Aiguo Wu, Wenzhi Ren,Xuehua Ma
21.    A kind of magnetic MFe2O4/C/M’composites and their synthetic methods based on phenylenediamine as carbon sources. 
(2011, Applied No.: CN 201110334595.0)
Inventors：Aiguo Wu, Xinmei Zhao
22.    A kind of magnetic MFe2O4/C/AOX composites and their synthetic methods based on catechol as carbon sources.
(2011, Applied No.: CN 201110397312.7)
Inventors：Wenzhi Ren, Aiguo Wu
23.    A kind of active targeting drug delivery system for cancer cells based on nanoparticles and theirs prepared method.
(2011, Applied No.: CN 201110334606.5)
Inventors：Xinmei Zhao, Aiguo Wu
24.    A highly sensitive colorimetric assay method for Co2+ detection. 
(2011, Applied No.: CN 201110363954.5) 
Inventors：Yumin Leng, Aiguo Wu
25.    A detection method of Cr(III) cations.
(2011, Applied No.: CN 201110337660.5)
Inventors： Junwei Xin, Aiguo Wu
26.    Fe3O4-TiO2 nanopcomposites: Preparation and application as contrast agents in magnetic resonance imaging.
(2010, Applied No.: PCT/CN2010/077803).
Inventors: Leyong Zeng, Aiguo Wu, Ping Cui
27.    A detection method of cations in aqueous solutions .
(2010, Applied No.: CN 200910152440.8)
Inventors: Leyong Zeng, Aiguo Wu 

III)    Invention Disclosures/Reports

(1) NU 26106:   Method for locating cells on microscopy grids 
      Inventors:  Aiguo Wu, Gayle E. Woloschak
(2) NU 26153: An approach to magnetic resonance imaging based on magnetic nanocrystals.  
    Inventors:  Aiguo Wu, Tatjana Paunesku, and Gayle E. Woloschak   
(3) NU 26154: Preparation of magnetic nanocrystal materials and the formation process of magnetic nanocomposite materials.  
    Inventors:  Aiguo Wu, Tatjana Paunesku, and Gayle E. Woloschak
(4) NU 26171: Preparation of core-corona-shell nanocrystal materials and the formation process of nanocomposite materials
    Inventors:  Aiguo Wu, Tatjana Paunesku, and Gayle E. Woloschak
(5) NU 26172:  Preparation of core-shell nanocrystal materials based on metal components and the formation process of nanocomposite materials including metal elements
    Inventors:  Aiguo Wu, Tatjana Paunesku, and Gayle E. Woloschak
(6) NU 27045:  An approach to computed tomography based on nanomaterials with photoactive properties 
      Inventors:  Aiguo Wu, Tatjana Paunesku, and Gayle E. Woloschak
(7) NU 27046:  An approach to computed tomography and magnetic resonance imaging obtained simultaneously based on nanomaterials
    Inventors:  Aiguo Wu, Tatjana Paunesku, and Gayle E. Woloschak
(8) NU200615302：Multifunction Nanoconjugates for Imaging Applications and Targeted Treatment 
    Inventors:  Aiguo Wu, Tatjana Paunesku, and Gayle E. Woloschak

3) Monograph
1.    Juan Li, Zheyu Shen, Xuehua Ma, Lingchao Xiang, An Gong, Tian Xia, Junming Guo and Aiguo Wu. The concentrations of neuropeptide Y and hexadecenoic acid in synovial fluid relate to structural severity and pain in patients with knee osteoarthritis, 2016, Elsevier Press, 7 pp.
2.    Mingqian Tan and Aiguo Wu. Nanomaterials for Tumor Tageting Theranostics, 2015 Higher Education Press, 53pp.
3.    Zhenzhi Shi, Yu Xu and Aiguo Wu. Advances in Nanotheranostics I, 2015, Springer Press, 103pp